One more research paper has just been published that shows how plant based compounds can help to contain the brittle bone condition, osteoporosis. Scientists at the Institute associated with Medical Sciences, University of Aberdeen, UK have discovered how a non-psychoactive compound in cannabis, cannabidiol helps to sustain bone strength.
The endocannabinoid system is a group of cell receptors that are activated by a group of endogenous lipids as well as compounds derived from the cannabis flower. The cannabinoid receptors are involved in a number of physiological processes including appetite manage, pain, memory and mood. Recent research has shown that the endocannabinoid system also has a strong influence on bone tissue metabolism, as the receptors are well displayed on osteoclasts – cells in whose principal function is to resorb (thin out) bone.
Bone is an energetic, living tissue that is being continually formed, remodeled and shaped in response to both physical and physiological requirements of the body. Bone matrix consists primarily of the macronutrients calcium, magnesium and phosphate and is the materials that makes up both the dense areas of the bone and the bone marrow framework. Many people still believe that in case one eats foods rich in these types of minerals then they will avoid establishing osteoporosis. Epidemiological and other evidence suggests that this is not necessarily the case.
When it comes to bone tissue health and disease the integrated processes that control the formation plus resorption bone are just as important as the availability of calcium, magnesium and phosphate.
The formation and resorbtion of bone matrix is managed by two main cell types:
1) Osteoblasts are bone cellular material that are responsible for the formation associated with bone matrix
2) Osteoclasts are modified white blood cells accountable for the resorption of bone cells.
These two cell types are managed by a complex set of signaling bodily hormones, proteins and cell receptors that respond to the ever-changing demands upon bone tissue and other physiological processes. If you have any questions pertaining to where and how to use bio cbd kaufen, you can get in touch with us at the internet site. If there are too many osteoclasts, or if these cells become overactive, they will resorb more matrix compared to osteoblasts can produce. A predominance of osteoclast activity results in the bone tissue becoming less dense – the principal characteristic of the clinical condition generally known as osteoporosis.
The Aberdeen researchers have discovered that cannabidiol binds to a specific cannabinoid receptor on the bone-resorbing osteoblast cells. By so doing it prevents these cells from resorbing the bone matrix – thereby assisting to prevent further weakening of the bones.
This is not the first time that plant compounds have been shown to influence bone metabolism in favour of stronger bones. In January 2009 researchers at Oklahoma State University in the USA found that, during the presence of oxidative stress and systemic inflammation, polyphenols derived from plums prevent the action of the bone-softening osteoclasts but enhance the generation and activity of bone-building osteoblasts.
For those who hope that smoking pot will help to strengthen their bones, they do so in vain. Although wild cannabis contains as much as 40% cannabidiol, cultivated varieties consist of very little of this compound. The important point arising from this research, in my opinion, is it shows how vital plant compounds are in the prevention of chronic degenerative illnesses such as osteoporosis. There are bound to end up being many other phytonutrients in other food plant life that have a positive influence on bone tissue metabolism – they just have not really been “discovered” yet.
While we wait for that research to be performed, it is important to eat (not smoke) a wide range of vegetables, fruit and spices to ensure an adequate intake of a host of beneficial phytonutrients.